Inhibition of CFU-NM and CFU-EOS by mature granulocytes

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Inhibition against CFU-C and CFU-E colony formation by soluble factor(s) derived from hairy cells.

The inhibitory effect by hairy cell conditioned medium (HCCM) on the growth of granulocyte and erythrocyte colony forming cells was studied in vitro. The percent inhibition of CFU-C formation by HCCM from four hairy cell leukemia (HCL) patients ranged from 36% to 76%, while no inhibition was observed with conditioned medium (CM) obtained from three B-cell chronic lymphocytic leukemia (B-CLL) pa...

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Loss of hematopoietic progenitor cells CFU-GEMM, BFU-E, CFU-Mk, and CFU-GM in the acquired immunodeficiency syndrome (AIDS)?

Hematological abnormalities have been found in the majority of patients with AIDS, in addition to immunological derangements [1]. Furthermore, treatment of opportunistic infections with folic acid antagonists and of neoplasms with cytostatic drugs is frequently complicated by profound thrombocytopenia, neutropenia, and anemia, thus resulting in the withdrawal of the drugs. In the present study ...

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To the editor : CFU

We read with interest the article “Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principles” by Yoder et al.1 The authors compared 2 types of colony assays that have been shown to identify endothelial progenitor cells (EPCs)2,3 and studied the function of the cells derived from these assay systems. They found that a commercially available kit...

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ژورنال

عنوان ژورنال: Blood

سال: 1984

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v63.2.376.376